ARMY AL&T
to develop and procure unprecedented COVID-19 diagnostic tests in record time. The delivery of BioFire’s COVID-19 test increases the DOD’s diagnostics capability and capacity and preserves the readiness of the joint force.
products are being developed in partnership with the Defense Advanced Research Projects Agency and the National Institutes of Health (NIH). Doses of these products will be accelerated for testing in clinical trials using this DOD capability and will be made available for early use by DOD personnel.
TREATMENT
In 2016, the JPEO-CBRND partnered with Gilead Sciences Inc. to develop remdesivir, a broad- spectrum antiviral, to combat outbreaks of viruses that may affect our warfighters. Peer-reviewed journals have reported that the drug shows activity against coronaviruses. This existing rela- tionship with a valued industry partner, along with the contributions of the JPEO-CBRND techni- cal team—to leverage the Medical CBRN Defense Consortium’s rapid contracting capability, request submissions from across the industry and then review over 500 white papers—have acceler- ated efforts to repurpose the drug as a COVID-19 treatment.
Recently, JPEO-CBRND cooperated with inter- agency partners who develop medical capabilities for public health protection to make remdesivir available under a clinical trial. The JPEO-CBRND worked with the U.S. Army Medical Research and Development Command’s U.S. Army Medical Materiel Development Activity to establish a force health protection protocol with the FDA so that both service members and civilian DOD person- nel who cannot participate in the NIH clinical trial have access to this treatment.
“Support from the Health Readiness Policy and Oversight office spurred our efforts ”
— Col. Ryan Eckmeier
Remdesivir is now available under this protocol at 23 military medical treatment facility sites world- wide, with at least 11 DOD personnel recovering from COVID-19 after receiving the treatment. The JPEO-CBRND is also implementing observational clinical studies, in which the investigator makes no intervention and patients are allocated treatment based on clinical decisions, inside and outside of the continental United States. These clinical studies, which leverage well-established DOD clin- ical research networks, provide a standardized approach to collecting clinical data across the mili- tary health system and with international partners. These efforts will lay the foundation for studies of therapeutic and prophylactic (vaccine) products.
“The JPEO-CBRND’s COVID-19 response efforts have demonstrated our ability to mitigate the harm caused by emerging biological threats, when and where it really counts. We are able to leverage and tailor existing agreements with our industry and interagency partners to rapidly bring medi- cal solutions to the fight against this pandemic,” Eckmeier said.
“We truly are all in this together,” he said. “While continuing the JPEO-CBRND's mission to bring much-needed CBRN defense equipment and medi- cal countermeasure capabilities to the joint force, the expertise and dedication of our workforce has allowed us to pivot quickly in support of an effi- cient and effective whole-of-government response to the COVID-19 pandemic.”
https://asc.ar my.mil
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